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华裔青年德里克・李（Derek Lee 饰）发现自己患了严重的疾病，从小热爱旅行的他决定不再浪费时间，他和担任电视制片人的好哥们克里夫・普劳斯（Clif Prowse 饰）一拍即合，两人决定进行为期一年的全球旅行，期间会将旅行中的点点滴滴录下来传到视频旅行博客上，和全世界的同好共享。起初一切顺利，谁知旅行的第七天发生了变故。德里克在巴黎搭上了一位美女，结果却被敲头，身上满是鲜血。在此之后，种种异状开始在德里克身上发生，他一连数日昏头大睡，在太阳下面颊出现烧伤症状，接着又变成可以打碎石头、狂奔超过摩托的超人。 　　诡异的旅程，遥遥没有尽头…… ©豆瓣

A scientist discovers the bodies of three frozen genetically modified Russians buried in the Canadian North. Upon thawing them out he realizes he has unleashed a deadly threat to Western society and must stop them at all costs.

Five university friends gather at a house party to ring in the New Year. Unbeknownst to them, an epidemic has erupted outside, causing outbreaks around the world. With nowhere else to turn, they barricade themselves indoors with only their phones, laptops, and other tech devices. They use their devices to research the possible cause of this outbreak. Information and video footage over flow their computers as they descend further into the cause and the ensuing chaos. As the virus spreads, the mood in the house changes from fear to paranoia. Who is safe? Who can they trust? Reality becomes blurred as they slowly discover the source of the virus causing the sickness...and there is no going back.